ESR project: Development of purification and modification strategies of N-type glycopeptide and glycan moieties
Supervisor: Dr Daniel Spencer
Institution: Ludger Ltd
Country of origin: Colombia
NanoCarb research: Javier will work as part of the production team at Ludger Ltd (Oxford, UK), on the isolation of N glycopeptides from natural sources, the isolated glycopeptides will be used at later stages within the consortium.
Dissemination and outreach:
- Gizem Erol, Patricia Pérez Schmidt, Alessia Pancaro, Javier M. Melo Diaz, Africa G. Barrientos, John Porter, Laura Polito, Michal Szymonik, Inge Nelissen, Daniel I.R. Spencer, Arianna Piotti, Marten Beeg, Maria-Grazia De Simoni, Stefano Fumagalli, Marco Gobbi. New nanostructures inhibiting human mannose binding lectin identified by a novel surface plasmon resonance assay, Sensors and Actuators B: Chemical, Volume 360, 2022, 131661. Open Access
- Javier M. Melo Diaz, Simon Peele, Daniel Spencer, Jenifer Hendel. Extraction and purification of a High Mannose type oligosaccharide from Phaseolus lunatus beans by oxidative release with sodium hypochlorite, Carbohydrate Research, 2022. Open Access.
- Javier M. Melo Diaz, Alan Moran, Simon Peele, Daniel Spencer, Jenifer Hendel. Egg yolk sialylglycopeptide: purification, isolation and characterization of N-glycans from minor glycopeptide species, Organic & Biomolecular Chemistry, 2022. Open Access.
Scientific background: Javier holds a bachelor’s degree in Chemistry from the Universidad Nacional de Colombia where he worked on the chemical synthesis of biologically active peptides (2016). After graduation he got a scholarship to take part of the 9th edition of the Erasmus Mundus master’s in quality of Analytical Laboratories (EMQAL) which was hosted by the Universidade do Algarve (Portugal), and the Universitat de Barcelona (Spain), (2016-2018). This program combined the technical and managerial modules that are needed for the quality management system of an analytical laboratory.