ESR 11 – Alessia Pancaro

ESR project: Biosensing platform for lectin detection related to cerebrovascular disease using nanoplasmonics

Supervisor: Dr Inge Nelissen

Institution: VITO, BE

Country of origin: Italy

NanoCarb research: Alessia will focus on the development of a nanoplasmonics-based biosensing platform using gold nanorods (GNRs) for the detection of lectin biomarkers in liquid biopsies for early-stage diagnostics of stroke. She will design and characterize GNRs conjugated with glycopolymers, assess glycopolymer-lectin binding properties and optimize of the localized surface plasmon resonance (LSPR)-based method for in vitro diagnostic detection of lectins in human serum samples.

Publications and dissemination material:

  1. Alessia Pancaro (ESR 11), Michal Szymonik, Panagiotis G. Georgiou (ESR 3), Alexander N Baker, Marc Walker, Peter Adriaensens, Jelle Hendrix, Matthew I. Gibson, and Inge Neliggen. The Polymeric Glyco-Linker Controls the Signal Outputs for Plasmonic Gold Nanorods Biosensors due to Biocorona FormationNanoscale, 2021. Open Access.
  2. Milica Velimirovic, Alessia Pancaro (ESR 11), Robert Mildner, Panagiotis G. Georgiou (ESR 3), Kristof Tirez, Inge Nelissen, Christoph Johann, Matthew I. Gibson, and Frank Vanhaecke. Characterization of Gold Nanorods Conjugated with Synthetic Glycopolymers Using an Analytical Approach Based on spICP-SFMS and EAF4-MALSNanomaterials 2021, 11, no. 10: 2720. Open Access.
  3. Alessia Pancaro (ESR 11), Michal Szymonik, Sarah Deville, Jelle Hendrix and Inge Nelissen. Biosensing platform for lectin detection using nanoplasmonicsDIATECH 2020, Leuven, BE, 27-29 January 2020. Poster
  4. Alessia Pancaro (ESR 11), Michal Szymonik, Panagiotis G. Georgiou (ESR 3), Alexander N Baker, Marc Walker, Peter Adriaensens, Jelle Hendrix, Matthew I. Gibson, and Inge Nelissen. The Nature of The Polymeric Glyco-Linker Controls the Signal Outputs for Plasmonic Gold Nanorods Biosensors in Complex Media due to Biocorona Formation. NanoMed Europe ’21 conference, 7-9 September 2021. Poster.

Scientific background: Alessia obtained a M.Sc in Molecular and Industrial biotechnology and a Bachelor’s degree in Biomolecular and Industrial biotechnology at the Università degli Studi di Napoli Federico II.